Scleroderma: From Therapeutic Nihilism to Therapeutic Optimism
نویسندگان
چکیده
Several types of inflammatory cells infiltrate the affected tissue. Different subsets of “T” lymphocyte may be observed in different affected organs in various stages of SSc. CD4 lymphocytes are increased in the affected skin, whereas CD8 lymphocytes are found more commonly in bronchoalveolar lavage of patients who have scleroderma-related interstitial lung disease (ILD). Several autoantibodies including anti-topoisomerase I (Scl 70) antibodies and anticentromere antibodies are detectable in scleroderma patients.
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